François Nosten Selected Research

artemisinin (artemisinine)

1/2022	Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response.
1/2021	Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness.
1/2020	Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis.
1/2020	Declining Burden of Plasmodium vivax in a Population in Northwestern Thailand from 1995 to 2016 before Comprehensive Primaquine Prescription for Radical Cure.
1/2020	Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis.
1/2019	Efficacy of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a protocol for systematic review and individual patient data (IPD) meta-analysis.
12/2018	The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background.
11/2018	Antimalarial drugs for treating and preventing malaria in pregnant and lactating women.
1/2018	Fitness Costs and the Rapid Spread of kelch13-C580Y Substitutions Conferring Artemisinin Resistance.
12/2017	Systematic literature review and meta-analysis of the efficacy of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: methodological challenges.

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François Nosten Research Topics

Disease

96	Malaria 04/2022 - 01/2002
59	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2021 - 11/2002
51	Infections 12/2021 - 11/2002
22	Vivax Malaria 10/2021 - 05/2003
9	Hemolysis 01/2020 - 12/2010
9	Glucosephosphate Dehydrogenase Deficiency 01/2020 - 12/2010
9	Parasitemia 07/2019 - 05/2007
6	Acute malaria 01/2015 - 12/2006
5	Spontaneous Abortion (Miscarriage) 12/2021 - 03/2002
5	Body Weight (Weight, Body) 01/2019 - 07/2006
5	Fever (Fevers) 11/2015 - 12/2002
4	Stillbirth 01/2020 - 03/2002
4	Birth Weight (Birth Weights) 01/2020 - 03/2002
2	Pregnancy Complications 12/2021 - 11/2002
2	Parasitic Diseases (Parasitic Disease) 01/2020 - 01/2017
2	Premature Birth (Birth, Premature) 01/2020 - 01/2019
2	Inflammation (Inflammations) 01/2019 - 11/2010
2	Congenital Abnormalities (Deformity) 11/2018 - 03/2002
2	Neonatal Hyperbilirubinemia 01/2018 - 01/2018
2	Scrub Typhus (Typhus, Scrub) 12/2015 - 04/2008
2	Pneumonia (Pneumonitis) 01/2013 - 01/2012
1	Torsades de Pointes (Torsade de Pointes) 01/2021
1	Kernicterus 01/2019
1	Syphilis 01/2019
1	Neonatal Jaundice 01/2017
1	Measles 01/2017
1	Hepatitis B 04/2016

Drug/Important Bio-Agent (IBA)

39	artemisinin (artemisinine)IBA 01/2022 - 05/2007
29	Antimalarials (Antimalarial Agents)IBA 10/2021 - 01/2002
29	ArtesunateIBA 10/2021 - 12/2002
23	artenimol (dihydroartemisinin)IBA 10/2021 - 05/2007
22	piperaquineIBA 10/2021 - 05/2007
21	Pharmaceutical PreparationsIBA 04/2022 - 01/2002
18	Chloroquine (Aralen)FDA LinkGeneric 10/2021 - 03/2002
14	Quinine (Quinson)FDA Link 01/2020 - 03/2002
13	Mefloquine (Lariam)FDA LinkGeneric 10/2021 - 12/2002
11	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 10/2021 - 02/2006
11	Primaquine FDA Link 01/2019 - 12/2010
9	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 01/2020 - 12/2010
8	AntigensIBA 06/2021 - 04/2008
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2012
7	VaccinesIBA 09/2020 - 04/2010
6	Lumefantrine FDA Link 10/2015 - 06/2006
5	Proteins (Proteins, Gene)FDA Link 06/2021 - 06/2004
4	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 06/2021 - 10/2009
4	C-Reactive ProteinIBA 06/2021 - 11/2015
4	Biomarkers (Surrogate Marker)IBA 06/2021 - 11/2010
4	Artemether FDA Link 01/2018 - 12/2006
4	AntibodiesIBA 05/2017 - 11/2012
4	proguanil drug combination atovaquone (malarone)FDA Link 09/2005 - 12/2002
3	Histidine (L-Histidine)FDA Link 06/2021 - 01/2019
3	InsecticidesIBA 01/2020 - 04/2010
3	Pyrethrins (Pyrethroids)FDA Link 01/2020 - 03/2017
3	pyrimethamine drug combination fanasil (Fansidar)FDA Link 01/2019 - 07/2014
3	Amodiaquine (Camoquin)FDA Link 01/2019 - 09/2011
3	Biological ProductsIBA 10/2017 - 05/2006
3	Immunoglobulin G (IgG)IBA 01/2017 - 12/2015
3	ArtemisininsIBA 05/2016 - 08/2011
2	Formaldehyde (Formol)FDA Link 04/2021 - 11/2010
2	SuspensionsIBA 01/2020 - 01/2019
2	hemozoinIBA 01/2020 - 11/2002
2	Clindamycin (Cleocin)FDA LinkGeneric 07/2019 - 04/2008
2	tafenoquineIBA 03/2018 - 02/2017
2	Recombinant ProteinsIBA 10/2017 - 01/2013
2	Immunoglobulin M (IgM)IBA 07/2017 - 12/2015
2	NITD 609IBA 01/2017 - 07/2014
2	TabletsIBA 01/2017 - 11/2006
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2017 - 01/2013
2	Pyrimethamine (Daraprim)FDA Link 08/2004 - 09/2003
1	Culture MediaIBA 01/2022
1	ethyl acetateIBA 04/2021
1	Ribosomal RNAIBA 01/2021
1	quinolineIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	cyhalothrinIBA 01/2020
1	Capsules (Microcapsules)IBA 01/2020
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2019
1	Indicators and Reagents (Reagents)IBA 01/2019
1	EnzymesIBA 03/2018
1	Dapsone FDA Link 03/2018
1	BilirubinIBA 01/2018
1	NucleotidesIBA 12/2017
1	Permethrin (Ambush)FDA LinkGeneric 03/2017
1	DDTIBA 03/2017
1	decamethrin (deltamethrin)IBA 03/2017
1	NADP (NADPH)IBA 02/2017
1	hepatitis B hyperimmune globulinIBA 01/2017
1	Scavenger Receptors (Scavenger Receptor)IBA 01/2017
1	Menthol FDA Link 01/2017
1	naphthaleneIBA 01/2017
1	LigandsIBA 01/2017
1	methyl 1- ribofuranosyl- 1,2,4- triazole- 3- carboxamidateIBA 06/2016
1	Hepatitis B e AntigensIBA 04/2016

Therapy/Procedure

13	Therapeutics 01/2020 - 01/2002
10	Prenatal Care (Care, Prenatal) 12/2021 - 11/2010
6	Chemoprevention 01/2019 - 03/2012
4	Aftercare (After-Treatment) 01/2016 - 07/2010
2	Mass Drug Administration 01/2017 - 01/2016
1	Duration of Therapy 01/2019
1	Cesarean Section (Caesarean Section) 01/2019